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diagnosis differential causes medications algorithm comparison hypokalemia management treatment binders diuretics high renal agents binding low metabolic pathophysiology patiromer urine
Key Characteristics of Old and New Potassium-Binding Agents - Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd #Potassium #Binding #KBinders #Kayexelate
edgarvlermamd #Potassium ... Kayexelate #Comparison #Table ... #Pharmacology # ... Patiromer #HyperKalemia ... #Nephrology #Agents
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Exogenous (KCL ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology ... #potassium #medications
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... Management of Hyperkalemia ... #treatment #pharmacology ... #table #comparison ... #nephrology
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Aldosterone Release: ACE ... happypillsrx/ #Hyperkalemia ... Pathophysiology #Pharmacology ... #Impaired #Potassium
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypokalemia Differential ... Hypertensive: • High Al ... Gitelman's syndrome #Hypokalemia ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat Hyperkalemia ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Causes of Hypokalemia Hypokalemia results from abnormal losses, transcellular shifts, or insufficient intake (Table 1).6–8 Abnormal losses
Causes of Hypokalemia ... Hypokalemia results ... insufficient intake (Table ... .9 Because the kidney ... significantly lower potassium
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 Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... treated with IV potassium ... differentiating kidney ... #differential #potassium ... #nephrology #low
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... ↑ Aldosterone: Kidney ... syndrome #hypokalemia ... #urine #potassium ... algorithm #diagnosis #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Hypokalemia ... Chronic progressive kidney ... Potassium-sparing ... ACE-Is and ARBs ... diagnosis #causes #nephrology
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