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Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
#Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... polystyrene sulfonate • Patiromer ... Hyperkalemia #treatment #pharmacology ... #table #comparison ... #nephrology
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
Veltassa (Patiromer ... ACE inhibitors, ... #Potassium #Binder ... #KBinder #Hyperkalemia ... #Pharmacology
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
Phosphate Binders ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology # ... Nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... ; hypokalemia Patiromer ... #medications #pharmacology ... #table #comparison ... #binders
Table 22 provides the characteristics of various phosphate-binding agents.
#Pharmacology #Nephrology #Phosphate #Phosphorus #Binders #Comparison #Table #Disadvantages
Table 22 provides ... #Pharmacology #Nephrology ... Phosphate #Phosphorus #Binders ... #Comparison #Table
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology # ... Nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Elimination (see Table ... Ca-gluconate or 1g CaCl ... effectiveness - Patiromer ... Management #Treatment #potassium ... #nephrology #K