7 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Aldosterone Release: ACE ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings
 • Feeling a "pop"
 • Acute
Cruciate Ligament (ACL ... Feeling a "pop" • Acute ... Lachman's test + Pivot ... AnteriorCruciateLigament #ACL ... #MSK #Sports #pathophysiology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
(Sens. 81% for acute ... effusions). 1/5 pts w/ acute ... endomyocardial biopsy Pharmacology ... : • ACE Inhibitors ... management #cardiology #pharmacology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... have fever - ACS ... , AKI, acute limb ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... bodies, shallow ACD ... damage & blindness Signs ... Photophobia #Acute ... ClosedAngle #Glaucoma #pathophysiology
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
Activation of ACC ... BZD #withdrawal #pharmacology ... #pathophysiology ... #diagnosis #signs