10 results
Lisinopril - ACE inhibitor used for the treatment of hypertension and heart failure. 3rd most prescribed
Lisinopril - ACE ... #Pharmacology #Lisinopril ... Prinivil #Qbrelis #ACEI ... Inhibitor #Overview #Review
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... differential #diagnosis #pathophysiology ... #pharmacology #
Heart Failure (HFrEF) Treatment - GDMT for stage C 

For patients with Heart Failure with REDUCED
initiate them on ACEI ... maximally tolerated ACEI ... recommended by the ACC ... /ambcarerx #CHF ... #HFrEF #Pharmacology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Heart Failure Medications Summary
Inhibitors of the Renin-Angiotensin System:
 • ACE Inhibitors: Benazepril, Captopril, Enalapril, Lisinopril, Quinapril,
Renin-Angiotensin System: • ACE ... #Medications #CHF ... #cardiology #pharmacology
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
Here’s a review ... classes (Aliskiren, ACEI ... Antagonists), all ... potassium, just like all ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
81% for acute HF ... endomyocardial biopsy Pharmacology ... : • ACE Inhibitors ... management #cardiology #pharmacology ... #sCHF
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
patients with CKD, HF ... ACE inhibitors, ... #Hyperkalemia #Pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Medications: K+, ACEi ... Na delivery): CHF ... offending medications (review ... Ca-gluconate or 1g CaCl
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
May have typical HF ... • Avoid ARB/ACE-I ... auto-transfusion and relief ... GDMT meds (e.g., ACE