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hematology management differential gammopathy chronic cll comparison hodgkins lupus lymphocytic lymphoma mgus significance sle syndrome workup algorithm anemia aplastic behcet
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... chemotherapy for low-risk disease ... fludarabine) 3) Monoclonal ... #oncology #hematology ... #hemeonc #diagnosis
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... - Differential Diagnosis ... Features: POEMS, AL ... Ig deposition disease ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... : ALL, CML, AML, ... extramedullary disease ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can indicate disease ... microglobulin Treatment ... #diagnosis #workup ... #oncology #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... involved) • No leukemic ... Differential Diagnosis ... NonHodgkins #comparison #oncology ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... : monoclonal TNF-aIpha ... signs #symptoms #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Evans • ITP • Cl-NH ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
: • Clinical Suspicion ... Management: • D/c all ... non-heparin A/C if clinical ... #Management #Treatment ... #Hematology #HemeOnc
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... Usually myeloid leukemias ... : - Seen with AML ... (~20 %) and APL ... #HemeOnc #Diagnosis
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
antibody - Early treatment ... deposition disease ... rituximab (in clinical ... Complications #diagnosis ... #hematology
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