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management chronic classification hemeonc leukemia rheumatology syndrome workup aecopd antinxp2 antinxp2dm apml cancer cell copd dermatology dermatomyositis differential differentiation disorders
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... uw_IMresidency #CLL ... #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Diagnosis: • ... microglobulin Treatment ... #workup #oncology ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... Responsive to Treatment ... pathophysiology #Hematology ... #Diagnosis #NonHodgkin
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... Imaging: CXR- pulmonary ... #management #hematology ... #oncology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD) Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... limitation (GOLD Ill ... of AECOPD: • Clinical ... #Exacerbation #treatment ... #pulmonary
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... salivary ducts Clinical ... UIP, NSIP): • Lymphocytic ... , INC risk PE, Pulmonary ... Adenocarcinoma Treatment
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
has five major clinical ... fungal stain of clinical ... count (mainly lymphocytes ... Hematopoietic stem cell ... becomes a yeast cell
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... syndrome): - Hematologic ... ± tocilizumab; call ... renal failure, pulmonary ... #HemeOnc #Diagnosis
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... Papillary carcinoma • Clear ... Dermatomyositis: • ILD was diagnosed ... positive patients Treatment ... Dermatomyositis #diagnosis
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