11 results
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Elevated Transaminases ... / Transaminitis ... - Differential ... Diagnosis • Infectious ... Diagnosis #causes #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Tests - Differential ... Alcoholic Hep, Drugs, Infection ... kwburak #LFTs #Elevated ... #Abnormal #Transaminitis ... Algorithm #diagnosis #hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... - Elevated Platelet ... Count - Differential ... : Chronic infections ... #Platelets #Differential
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Levels: > 50x normal ... - Infection (EBV ... Liver #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
or slightly elevated ... early on but elevated ... bile ducts Differential ... fungal, viral infections ... diagnosis #workup #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... - If both are normal ... of ALP • Near normal ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
if WBC > 5 or elevated ... initiation • Differential ... Diagnosis: Infection ... 500 mg QD until normal ... diagnosis #management #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Liver Injury: • Infectious ... specificity to elevated ... function may be abnormal ... diagnosis #algorithm #hepatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... vasculitis vs infection ... 50 in GCA, but normal ... complaints- anemia, thrombocytosis ... , transaminitis,
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... products that define normal ... Inflammatory marker elevated ... Immunohistochemical studies (to differentiate ... classification #hematology