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differential kidney acute aki algorithm causes comparison glomerulonephritis injury amyloid biopsy classification clinical deposits electronmicroscopy gbm glomerulus locations membranoproliferative microscopy
Kidney Biopsy - Diagnosis Algorithms 1) Normal Glomerulus by LM 2) Glomerular Crescents 3) Double Contours of GBM 4) Endocapillary
Kidney Biopsy - Diagnosis ... by LM 2) Glomerular ... Double Contours of GBM ... Kidney #Biopsy #renal ... #nephrology #pathology
Spectrum of Glomerular Diseases Nephrotic - Mechanism: • Injury to podocytes • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... Deposition of matrix ... • Breaks in GBM ... #spectrum #diagnosis ... #nephrology #nephritic
This image shows portions of glomerular tuft with collapsed GBM (across top), spicular amyloid (middle right),
shows portions of glomerular ... desposition #deposits ... ElectronMicroscopy #SEM ... #clinical #nephrology ... #pathology
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 Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
vascular supply; glomerular ... and interstitial disease ... GBM, Glomerular ... #Diagnosis #AKI ... Causes #Sites #Nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... (Dense deposit disease ... immune deposits on EM ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
- Differential Diagnosis ... • Vascular • Glomerular ... Immune-complex disease ... , Anti-GBM • Tubular ... #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria ... staining on IF • No EM ... #Differential #Diagnosis ... #Nephrology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... Electron Microscopy (EM ... #diseases #nephrology ... #pathology #comparison ... #table #diagnosis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... sclerosis • Anti-Glomerular ... anti-ANCA ab, anti-GBM ... #differential #diagnosis ... #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... • Drugs Glomerular ... Minimal change disease ... • Protein deposition ... #Proteinuria #Nephrology
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