12 results
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
Hematuria Important ... RBC’s, RBC/WBC casts ... , proteinuria suggest ... intrinsic renal disease ... prostatic) #Diagnosis #EM
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... syndrome—due to GBM ... hematuria. ... Nephrotic #Syndromes #Classification ... #Proteinuria #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... Minimal change disease ... #Nephrology #Differential ... #Diagnosis #Algorithm
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... disease • ... • Pauci-immune disease ... nephrotic range) proteinuria
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
basement membrane disease ... Brown urine - Proteinuria ... of glomerular disease ... microscopic and ... #urology #nephrology
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach ... eosinophiluria, microscopic ... hematuria, mild ... tubular proteinuria ... #nephrology #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
of glomerular disease ... (hematuria, proteinuria ... Basement Membrane (GBM ... Glomerulonephritis #RPGN #Classification ... Differential #Diagnosis #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... Cytomegalovirus; GBM ... Nephrocalcinosis causes ... Hematuria may be ... nephrotic #syndrome #nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Dyspnea, Fever, Hematuria ... polyangiitis, Microscopic ... • Urinalysis (proteinuria ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... , hematuria) • ... Goodpasture's cause ... or gross hematuria ... grade proteinuria