18 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
syndrome—due to GBM ... hematuria. ... RBC casts in urine ... Nephrotic #Syndromes #Classification ... #Proteinuria #Nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
• Evidence of glomerular ... bleeding (proteinuria ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
and/or proteinuria ... the patient have glomerular ... casts or dysmorphic ... RBCs in urine)? ... Comparison #Algorithm #Nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... of Glomerular Bleeding ... • Signs of glomerular ... - Proteinuria ... #urology #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Drugs Glomerular ... proliferative • Anti-GBM ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria ... , proteinuria) ... Glomerulonephritis #RPGN #Classification ... Differential #Diagnosis #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... blood cells on urine ... • Calculi Glomerular ... ) • Anti-GBM ... nephrotic range) proteinuria
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... arbitrarily defined as urine ... because nephritic urine ... Hematuria may be ... #syndrome #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
disease 24-hour urine ... Spot PC (protein ... Serum or urine for ... infections are common causes ... nephrotic #nephritic #nephrology
Causes Abnormal Urine Color - Differential Diagnosis
Turbid White Urine (Albinuria):
 • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Causes Abnormal ... Hyperoxalirua, Heavy Proteinuria ... : • Hematuria, ... : • Hematuria, ... Differential #Diagnosis #nephrology