20 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
to GBM disruption ... hematuria. ... RBC casts in urine ... #Classification ... #Proteinuria #Nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient has hematuria ... and/or proteinuria ... (RBC casts or dysmorphic ... RBCs in urine)? ... Comparison #Algorithm #Nephrology
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
- Normal/low Proteinuria ... - ++++ Hematuria ... - ++ Hematuria ... edgarvlermamd - Nephrology ... Comparison #Table #Nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... glomerular bleeding (proteinuria ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... blood cells on urine ... • Hereditary nephritis ... and >3.5g/day (nephrotic ... range) proteinuria
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
: Red/Dark urine ... 1ml blood/liter urine ... examination of urine ... - Proteinuria ... #urology #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... (Negative urine ... proliferative • Anti-GBM ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Acute Interstitial Nephritis ... eosinophiluria, microscopic hematuria ... , mild tubular proteinuria ... #Interstitial #Nephritis ... AIN #Algorithm #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... urine sediment ... Hematuria may be ... #nephrotic #syndrome ... #nephrology
Albuminuria (Grades) and Risk for CKD
Normal to mildly increased albuminuria:
 - Albumin excretion rate: < 30
Nephrotic-range ... Urine total protein ... is defined as nephrotic ... Albuminuria #Grades #classification ... #CKD #nephrology