12 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... syndrome—due to GBM ... hematuria. ... Nephrotic #Syndromes #Classification ... #Proteinuria #Nephrology
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
RBC’s, RBC/WBC casts ... , proteinuria suggest ... intrinsic renal disease ... prostatic) #Diagnosis #EM ... #IM #Urology #Hematuria
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... glomerular bleeding (proteinuria ... → Refer to Nephrology ... if cause not identified ... #Workup #urology
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... disease • ... nephrotic range) proteinuria ... #Causes
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... Minimal change disease ... #Nephrology #Differential ... #Causes
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
basement membrane disease ... Brown urine - Proteinuria ... of glomerular disease ... Bladder Causes ... #urology #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
of glomerular disease ... (hematuria, proteinuria ... Basement Membrane (GBM ... Glomerulonephritis #RPGN #Classification ... Differential #Diagnosis #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... Cytomegalovirus; GBM ... Nephrocalcinosis causes ... Hematuria may be ... nephrotic #syndrome #nephrology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
toxo IgG • CNS PCR ... granulomatosis: • EBV-associated ... lymphoproliferative disease ... differential #diagnosis #causes ... #radiology #neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
multiplex • Hematuria ... , proteinuria, rapidly ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... #rheumatology #classification