27 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
syndrome—due to GBM ... hematuria. ... RBC casts in urine ... Proteinuria often ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient has hematuria ... and/or proteinuria ... (RBC casts or dysmorphic ... Comparison #Algorithm #Nephrology ... #Diagnosis
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
- Normal/low Proteinuria ... - ++++ Hematuria ... - ++ Hematuria ... edgarvlermamd - Nephrology ... #Diagnosis
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Diagnosis Framework ... → Diagnostic of ... Brown urine - Proteinuria ... #Differential #Diagnosis ... #nephrology #renal
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... glomerular bleeding (proteinuria ... → Refer to Nephrology ... if cause not identified ... #Diagnosis #Algorithm
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... - Differential Diagnosis ... proliferative • Anti-GBM ... #Nephrology #Differential ... #Diagnosis #Algorithm
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... - Differential Diagnosis ... nephrotic range) proteinuria ... #Differential #Diagnosis ... #Algorithm #Causes
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
and Differential Diagnosis ... of Macroscopic Hematuria ... RBC’s, RBC/WBC casts ... , proteinuria suggest ... #EM #IM #Urology
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
eosinophiluria, microscopic hematuria ... , mild tubular proteinuria ... , granular casts ... AIN #Algorithm #nephrology ... #diagnosis
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Chorioretinitis • Diagnosis ... PCR 50% sensitive ... #differential #diagnosis ... #causes #radiology ... #neurology