41 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
to GBM disruption ... hematuria. ... RBC casts in urine ... Proteinuria often ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient has hematuria ... and/or proteinuria ... (RBC casts or dysmorphic ... Comparison #Algorithm #Nephrology ... #Diagnosis
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
glomerular bleeding (proteinuria ... → Refer to Nephrology ... and referral to Urology ... cystoscopy • Refer to Nephrology ... #Workup #urology
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
- ++++ Hematuria ... - ++ Hematuria ... edgarvlermamd - Nephrology ... Comparison #Table #Nephrology ... #Diagnosis
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
and Differential Diagnosis ... of Macroscopic Hematuria ... RBC’s, RBC/WBC casts ... , proteinuria suggest ... #EM #IM #Urology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Diagnosis Framework ... syndrome: • ... Brown urine - Proteinuria ... #causes #urology ... #nephrology #renal
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... - Differential Diagnosis ... • Fanconi's syndrome ... #Nephrology #Differential ... #Causes
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Chorioretinitis • Diagnosis ... - Compatible syndrome ... PCR 50% sensitive ... #causes #radiology ... #neurology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
glomerular disease (hematuria ... , proteinuria) ... staining on IF • No EM ... #Differential #Diagnosis ... #Nephrology
Localizing Extraocular Movement Disorders
 • CN Ill (Oculomotor) Nerve Palsy 
 • CN IV (Trochlear) Nerve
Nerve Palsy • CN ... One-and-a-half Syndrome ... Skew Deviation Casey ... ophthalmology #neurology ... #differential #diagnosis