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diagnosis differential algorithm renal classification nephrotic neurology syndrome blood glomerulonephritis infections nephritic pulmonary rheumatology syndromes urine urology vasculitis aids brain
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... syndrome—due to GBM ... hematuria. ... diabetes)) #Glomerular ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
and/or proteinuria ... the patient have glomerular ... hematuria (RBC ... casts or dysmorphic ... Comparison #Algorithm #Nephrology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... of Glomerular Bleeding ... • Signs of glomerular ... Brown urine - Proteinuria ... #urology #nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... • Calculi Glomerular ... epithelial side of glomerular ... ) • Anti-GBM ... nephrotic range) proteinuria
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria ... , proteinuria) ... immune deposits in glomeruli ... Differential #Diagnosis #Nephrology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
• Evidence of glomerular ... bleeding (proteinuria ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Drugs Glomerular ... proliferative • Anti-GBM ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
proteinuria. ... Cytomegalovirus; GBM ... Nephrocalcinosis causes ... Hematuria may be ... #syndrome #nephrology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... PCR 50% sensitive ... granulomatosis: • EBV-associated ... differential #diagnosis #causes ... #radiology #neurology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Dyspnea, Fever, Hematuria ... sclerosis • Anti-Glomerular ... • Urinalysis (proteinuria ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
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