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diagnosis differential algorithm glomerular renal glomerulonephritis nephritic rheumatology syndrome workup acute classification cns comparison diseases management nephritis neurology urine urology
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
the patient has hematuria ... and/or proteinuria ... have glomerular hematuria ... (RBC casts or dysmorphic ... Comparison #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
to GBM disruption ... hematuria. ... RBC casts in urine ... Proteinuria often ... #Nephrology #Diagnosis
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome == Nephrotic Syndrome == Onset - Insidious Edema - ++++ Blood
- Normal/low Proteinuria ... - ++++ Hematuria ... pressure - Raised Proteinuria ... - ++ Hematuria ... edgarvlermamd - Nephrology
Glomerular Diseases - Spectrum - Insidious vs Acute - Nephritic (hypertension, hematuria, renal failure) vs Nephrotic
Insidious vs Acute - Nephritic ... (hypertension, hematuria ... renal failure) vs Nephrotic ... (Heavy proteinuria ... differential #diagnosis #nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... • Hereditary nephritis ... and >3.5g/day (nephrotic ... range) proteinuria ... Diagnosis #Algorithm #Causes
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Acute Interstitial Nephritis ... eosinophiluria, microscopic hematuria ... , mild tubular proteinuria ... #Interstitial #Nephritis ... AIN #Algorithm #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... Nephrocalcinosis causes ... Hematuria may be ... #nephrotic #syndrome ... #nephrology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Brown urine - Proteinuria ... and SMA - Can cause ... Bladder Causes ... urinary tract) Causes ... #urology #nephrology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... glomerular bleeding (proteinuria ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... sediment - WBC/RBC casts ... proliferative • Anti-GBM ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
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