9 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient has hematuria ... and/or proteinuria ... (RBC casts or dysmorphic ... RBCs in urine)? ... Comparison #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
to GBM disruption ... hematuria. ... RBC casts in urine ... Proteinuria often ... #Nephrology #Diagnosis
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
→ Refer to Nephrology ... and referral to Urology ... cystoscopy • Refer to Nephrology ... if cause not identified ... Algorithm #Workup #urology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
: Red/Dark urine ... 1ml blood/liter urine ... examination of urine ... - Proteinuria ... #urology #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... urine sediment ... Hematuria may be ... #nephrotic #syndrome ... #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
cryoglobulins, hepatitis serology ... , HIV serology, ... • Interstitial nephritis ... Differential #Diagnosis #nephrology ... #causes
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... dysmorphic RBC, RBC casts ... , +/- proteinuria ... glomerulopathy, radiation nephritis ... Glomerulonephritis #MPGN #nephrology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
toxo IgG • CNS PCR ... granulomatosis: • EBV-associated ... RingEnhancing #Lesions #Brain ... differential #diagnosis #causes ... #radiology #neurology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
virus • CMV • EBV ... Photophobia • Nausea ... established by CSF or urine ... culture or by serology ... differential #diagnosis #neurology