45 results
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Brown urine - Proteinuria ... Causes of Hematuria ... thrombosis • Renal ... #urology #nephrology ... #renal #urine #
Glomerular Diseases - Spectrum
 - Insidious vs Acute
 - Nephritic (hypertension, hematuria, renal failure) vs Nephrotic
(hypertension, hematuria ... , renal failure) ... Nephrotic (Heavy proteinuria ... differential #diagnosis #nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
glomerular bleeding (proteinuria ... → Refer to Nephrology ... for renal biopsy ... cystoscopy • Refer to Nephrology ... if cause not identified
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
syndrome—due to GBM ... hematuria. ... RBC casts in urine ... Proteinuria often ... #Nephrology #Diagnosis
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
of Macroscopic Hematuria ... RBC’s, RBC/WBC casts ... , proteinuria suggest ... intrinsic renal ... prostatic) #Diagnosis #EM
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
- Normal/low Proteinuria ... - ++++ Hematuria ... pressure - Raised Proteinuria ... - ++ Hematuria ... edgarvlermamd - Nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient has hematuria ... and/or proteinuria ... have glomerular hematuria ... (RBC casts or dysmorphic ... Comparison #Algorithm #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... sediment - WBC/RBC casts ... proliferative • Anti-GBM ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... nephropathy • Thin GBM ... ) • Anti-GBM ... nephrotic range) proteinuria ... Diagnosis #Algorithm #Causes
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
Renal involvement ... presentation • Hematuria ... - 97% • Mean proteinuria ... TerrierBen #Renal ... Cryoglobulinemic #Nephrology