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diagnosis electronmicroscopy neurology sem differential management glomerulus causes treatment algorithm gbm glomerular glomerulonephritis cns membranous rheumatology syndrome tuft anemia crescent
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
feel weak": • Infectious ... : Influenza, EBV ... Rhabdomyolysis, Critical ... illness, Infection ... Diagnosis #causes #neurology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
toxo IgG • CNS PCR ... granulomatosis: • EBV-associated ... splenomegaly Other infections ... multiple lesions Infectious ... causes #radiology #neurology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
cryoglobulinemia, post-infectious ... GN Anti-Glomerular ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... Differential #Diagnosis #Nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Vasculitis • GN ... : ANCA, Anti-GBM ... AIN: Medication, Infection ... Differential #Diagnosis #nephrology
Stage II Membranous Glomerulonephritis on Electron Microscopy This eyeSCANdy image shows acellular scanning EM of a glomerulus
acellular scanning EM ... appearance of GBM ... glomerulonephritis #MGN ... #SEM #clinical ... #nephrology #pathology
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 CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
should be based on clinical ... Toxoplasma gondii PCR ... • JC-virus PCR ... effect/Edema • EBV ... InfectiousDiseases #Neurology
Stage III Glomerulonephritis on Electron Microscopy This image shows acellular scanning EM from a biopsy with membranous
acellular scanning EM ... more extensive GBM ... glomerulonephritis #MGN ... #SEM #clinical ... #nephrology #pathology
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 Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... +++: Virus (EBV, ... biologics (CMV +++, EBV ... Etoposide/VP16 (100 mg
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Donath-Landsteiner Antibodies[PCH ... - Due to Viral infection ... Clinical Presentation ... - Mycoplasma, EBV ... Hemoglobinuria (PCH
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Membranoproliferative GN ... proliferative • Anti-GBM ... HSP • Post-infectious ... GN - Bland urine ... #Proteinuria #Nephrology
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