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diagnosis management hematology neurology differential hemophagocytic hlh lymphohistiocytosis aids brain cardiomyopathy cell cerebritis classification coagulation crypto cryptococcal dic disseminated erythematosus
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... autoantibodies that will cause ... #neurology #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... • Autoimmune diseases ... Treatment: • ... #summary #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
should be based on clinical ... Antimicrobial treatment ... Demyelinating disease ... caused by the JC ... effect/Edema • EBV
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... Thromboembolism (7%) • CNS ... • Severe Liver Disease ... Treat primary cause ... #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... • 8%-27% for CNS ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... Brucellosis - Dengue, EBV ... MCTD - Bechet disease ... Transverse Myelitis Treatment
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Clinical • Under-recognized ... teratogenic GDMT meds ... diagnosis #management #cardiology ... #treatment
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Hodgkin Lymphoma - Clinical ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
populations) CLINICAL ... CNS involvement: ... Birbeck granules (EM ... TREATMENT OPTIONS ... with appropriate treatment
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... Infections (e.g., EBV ... ▪ Autoimmune diseases ... Clinical Presentation ... Diagnosis #Management #Hematology
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