8 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
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Causes of Extravascular ... Hemolysis - Differential ... immune-complex hemolytic anemia ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... Microangiopathic hemolytic anemia ... #Causes #differential ... #diagnosis #hematology ... #anemia
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... - Differential ... malignancies • Anemia ... #Differential # ... #hematology #secondary
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - ... Differential Diagnosis ... Reactive: • Anemia ... Diagnosis #causes ... #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential ... Iron deficiency anemia ... #Differential # ... #Hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... IVIG infusion Intravascular ... #Differential # ... classification #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... reflection of intravascular ... immune hemolytic anemia ... WBC count and differential ... Diagnosis #Workup #Hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... systemic complaints- anemia ... , thrombocytosis ... GCA #Temporal #Signs