26 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... distal tubule. ↑ Nacl ... H+ secretion → Hypokalemia ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... MunerMohamed1 #hyperkalemia ... #differential # ... diagnosis #pathophysiology ... #medications #druginduced
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Bartter's syndrome, Gitelman's ... syndrome #Hypokalemia ... #Differential # ... Diagnosis #Algorithm #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Bartter syndrome, Gitelman ... @priti899 #Hypokalemia ... #Differential # ... potassium #low #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... • Cell shift: Hypokalemic ... Bartter syndrome, Gitelman ... urine #potassium #differential ... algorithm #diagnosis #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Once pseudohypokalemia is ruled out, causes of hypokalemia can be
Causes of Hypokalemia ... - Differential ... that is leaky all ... #Differential # ... Causes #workup #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... ratio 0.5%) Differential ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... - Differential ... Bartter's syndrome, Gitelman's ... #differential # ... algorithm #causes #nephrology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Hypomagnesemia - Differential ... Bartter syndrome and Gitelman ... with secondary, hypocalcemia ... Hypomagnesemia #differential ... diagnosis #causes #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... • High Urine Cl ... Bartter Syndrome, Gitelman ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #nephrology