11 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Pathophysiology ... complete paralysis of all ... Treatment: • Plasmapheresis ... Syndrome #diagnosis #management ... #treatment #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... complete paralysis of all ... the underlying pathophysiology ... and cauda equina TREATMENT ... Syndrome #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... have fever - ACS ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... functional ID) Treatment ... composite endpoint of all-cause ... heartfailure #diagnosis #management
Vasospastic (Prinzmetal) Angina
Definition / Epidemiology:
 • Rest angina attributed to coronary artery vasospasm.
 • Patients often
younger than other ACS ... Pathophysiology: ... tests in cath lab Treatment ... cardiology #diagnosis #management
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Diagnosis and Management ... Perforation) Pathophysiology ... - produced by all ... despite appropriate treatment ... IDSA 2021 CDI Treatment
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... ♀, ↑Age, ESRD Pathophysiology ... Management: • ... D/c all heparin ... #Treatment #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... Pathophysiology ... Renal Failure Treatment ... APML #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... circulation: MCA ACA ... epilepticus Treatment ... underlying cause • Treatment ... Syndrome #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... • In all patients ... search for and treatment ... Pathophysiology ... Treatment Approach