15 results
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• NSAIDs • ACE ... • Recent IV potassium ... Beta blockers • Antibiotics ... - Metabolic acidosis ... #high #nephrology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Potassium Excretion ... Aldosterone Release: ACE ... Decreased Na, K-ATPase ... Pathophysiology #Pharmacology ... #Renal
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• NSAIDs • ACE ... • Recent IV potassium ... Beta blockers • Antibiotics ... - Metabolic acidosis ... #high #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
loss • Renal ... hypokalemia • Renal ... tubular acidosis ... algorithm #causes #nephrology ... #potassium
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... suggests extra-renal ... - Metabolic acidosis ... #differential #potassium ... #nephrology #low
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Epithelial Cells Renal ... syndrome - Na-K- ... , K channel, Cl ... tubular acidosis ... Defects #Kidney #Nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
NSAIDs, β-blockers, Antibiotics ... - Renal Failure ... Ca-gluconate or 1g CaCl ... Management #Treatment #potassium ... #nephrology #K
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
oxoproline) • Renal ... Renal acidosis ... Potassium-sparing ... ACE-Is and ARBs ... diagnosis #causes #nephrology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
130 mEq/L • Potassium ... trial • Minimal K ... filtration - Renal ... blood flow and renal ... NS #comparison #pharmacology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
(AG) = {Na - (Cl ... salicylates) R Renal ... failure (uremia) K ... - Diarrhea - Renal ... Diagnosis #Summary #Nephrology