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management rheumatology pathophysiology differential erythematosus lupus sclerosis sle ankylosingspondylitis autoantibodies autoimmune bilateral blines cardiology checklist clinical complications crisis criticalcare heartfailure
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... skin thickening Signs ... (interstitial lung ... #rheumatology #diagnosis ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... effusion, Restrictive lung ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis
Bilateral B-Lines in case of Pneumonia on Lung POCUS Young healthy pt with fever/dyspnea. POCUS lung exam
POCUS lung exam ... disease, interstitial ... partially seen shred sign ... NOT definitively diagnose ... #ultrasound
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 Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Myositis 4% - Lung ... sclerosis, Still's disease ... autoantibodies #signs ... #symptoms #mimickers
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
cause interstitial lung ... disease/pulmonary ... pathophysiology #signs ... #symptoms #diagnosis ... #ExtraArticular
Heart failure with Reduced Ejection Fraction (HFrEF) Clinical Presentation 1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
More Specific Signs ... Less Specific Signs ... Chest x-ray: signs ... acute HF → no signs ... coronary artery disease
Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees) • Incr Axial rotation of thoracic
volume -> Decr lung ... Restrictive Pulmonary Disease ... pathophysiology #msk ... #diagnosis #signs ... #symptoms
Myasthenic Crisis Checklist - Myasthenia Gravis Evaluation - Chest X-ray and lung ultrasound (exclude other lung
ultrasound (exclude ... other lung disease ... or TSH level if symptoms ... Pyridostigmine - New diagnosis ... monitoring (vital signs
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
granulomas within the lungs ... the lymphatic system ... anterior/posterior MSK ... 5-10%, nervous system ... #Management #Signs
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