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diagnosis differential treatment hematology nephrology algorithm signs symptoms clinical disease pharmacology video weakness barre fatigue gravis guillain oncology posterior renal
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
crises”. ... immunologic assay - MuSK ... Crises - Severe ... Gravis #diagnosis #management ... #neurology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Causes of Peripheral ... Oculomotor • Myasthenia ... Lambert-Eaton Myasthenic ... Syndrome • Botulism ... Peripheral #Weakness #Neurology
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Demyelinating Disease (MS ... Guillain-Barre syndrome ... , Myasthenia Gravis ... differential #diagnosis #neurology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Cardiovascular Causes ... Hepatopulmonary syndrome ... Other Causes ... Neuromuscular: - Myasthenia ... Transverse myelitis • Hematology
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
antibodies - MuSK-positive ... likely to cause ... glucocorticoids - can cause ... Gravis #diagnosis #management ... #neurology #treatment
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Pulmonary Disease Neurologic ... Parkinson's • Myasthenia ... Chronic Fatigue Syndrome ... Diagnosis #Algorithm #causes
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... Other brainstem syndromes ... erythematosus, Sjögren syndrome ... , Myasthenia gravis ... Manifestations #diagnosis #neurology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... tremor, ataxia, asthenia ... • Neurologic ... diplopia, ataxia, asthenia ... Systemic effect -> Nausea
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
- Bickerstaff syndrome ... symptoms similar to myasthenia ... opsoclonus-myoclonus syndrome ... Differential #Diagnosis #Causes ... #Neurology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... old, ~10,000 new cases ... Myelodysplastic #Syndrome ... #treatment #hematology
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