27 results
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... and Benefits in ... number of pain crises ... #SickleCell #pathophysiology ... #pharmacology
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
Curve Left Shift ... Hypophosphatæmia Right Shift ... Dissociation #Curve #Pathophysiology ... #Left #Right #Shift ... #Differential #Causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... Diagnosis #Algorithm #causes ... potassium #low #pathophysiology
Conceptual Relationship between Volume Responsiveness and Volume Tolerance

Assessing for volume responsiveness would only tell you that
Causes of "Left ... Shift" (Decreased ... Tolerance #IVFluids #Shift ... #Differential #Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... differential #diagnosis #pathophysiology ... #pharmacology #
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Hydroxychloroquine - Risks and Benefits ... in Lupus Benefits ... rare with ~100 cases ... Hydroxychloroquine #hcq #Risks #Benefits ... #Lupus #pharmacology
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAIDs cause vasoconstriction ... use shouldn't cause ... kidney protective benefits ... Nephrology #Renal #Pathophysiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Electrolyte/fluid shifts ... caused by initiation ... • These shifts ... changes and may cause ... Differential #Diagnosis #Pathophysiology
AACE/ACE 2016 Postmenopausal Osteoporosis Treatment Algorithm

Evaluate for causes of secondary osteoporosis

Correct calcium/vitamin D deficiency and address
Evaluate for causes ... deficiency and address causes ... • Recommend pharmacologic ... fall prevention, benefits
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-induced edema is caused ... Edema #Medication #Causes ... #Differential #Pharmacology ... #Pathophysiology