20 results
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... admission to the ICU ... PLEX and RTX • Short-term ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology
Post-Intensive Care Syndrome (PICS)
Symptoms of PICS:
 - Physical Domain: Generalized weakness, Fatigue, Difficulty walking
 - Cognitive
Post-Intensive Care Syndrome ... guide targeted treatments ... IntensiveCare #Syndrome ... PICS #diagnosis #management ... #criticalcare #
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
block • Sjogren syndrome ... severe disease Treatment ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology ... #management
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Total scores >2 ... due to short half-life ... Propofol infusion syndrome ... #CriticalCare # ... diagnosis #management
The rationale for aggressive treatment of generalized status epilepticus was described previously here.  In short,
for aggressive treatment ... In short, best outcomes ... #Management #Neurology ... #CriticalCare #
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management ... #treatment
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... : - Bedside: ice ... Gravis #diagnosis #management ... #neurology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... organ dysfuxtion, ICU ... APML #diagnosis #management ... #hematology #oncology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... • Weakness: Starts ... Treatment: • Plasmapheresis ... #diagnosis #management ... #treatment #neurology
10 Steps to Managing Guillain-Barre Syndrome:
1️⃣ When to suspect
2️⃣ How to Diagnose
3️⃣ When to admit to
Guillain-Barre Syndrome ... When to admit to ICU ... When to start Treatment ... 5️⃣ Treatment ... #Management #Neurology