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diagnosis algorithm pituitary growthhormone acromegaly anemia beriberi comparison deficiency excess feedbackloop glftap hospitalization hypoglycemia hypokalemia insulinoma korsakoff low macroadenoma management
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... deficiency: - Short ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... • Other rare causes ... signs #symptoms #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
malignancy Pathophysiology ... Differential Diagnosis ... or refractory cases ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Differential Diagnosis ... Cushing's Disease • GH ... #ShortStature #Differential ... Diagnosis #Algorithm #endocrinology ... #causes #pediatrics
Sellar / Pituitary Mass - Differential Diagnosis Algorithm Adenoma - Primary Anterior Pituitary - Secreting
Pituitary Mass - Differential ... Prolactin • GH ... SellarMass #Pituitary #Differential ... Diagnosis #Algorithm #endocrinology ... #causes
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... - Differential ... K-ATPase which imports ... #Hypokalemia #Differential ... potassium #low #pathophysiology
Weight Gain / Obesity - Differential Diagnosis Algorithm Decreased Expenditure: • Sedentary Lifestyle • Smoking Cessation
Gain / Obesity - Differential ... Hypogonadism • GH ... WeightGain #Obesity #Differential ... Diagnosis #Algorithm #endocrinology ... #causes
Tall Stature - Differential Diagnosis Algorithm Normal Growth (BA=CA) • Familial Tall Stature • XYY Syndrome Obese BMI
Tall Stature - Differential ... Puberty Onset • GH ... #TallStature #Differential ... Diagnosis #Algorithm #endocrinology ... #causes
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
For pituitary masses ... following order; GH ... Headaches • Nausea ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Hypoglycemia Workup and Differential Diagnosis Workup: • Sulfonylurea Labs • Anti-lnsulin Ab - Insulin Autoimmune Syndrome •
Hypoglycemia Workup and Differential ... metabolic demand causes ... Normally, glucose stores ... still rise by 25+ Differential ... Diagnosis #insulinoma #endocrinology
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