9 results
diagnosis management differential hematology causes anemia hemolysis hemolytic intravascular sle summary treatment algorithm bleeding bruising classification comparison erythematosus hemophagocytic hemostasis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
vs Extravascular ... coagulation (DIC ... usually IgG) (e.g. lupus ... • Infections: Malaria ... differential #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Infections • Malaria ... • MAHA (TTP, DIC ... #Extravascular ... Algorithm #Causes #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... & NPSLE rare, Malar ... Manifestations: Malar ... Lupusreference #druginduced ... #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar ... , oral ulcers, Lupus ... of SLE versus DIL ... Management #Summary #rheumatology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Bartonella, Babesia, Malaria ... IVIG infusion Intravascular ... MAHA: TTP, HUS, DIC ... classification #hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... : -10% of all lupus ... & NPSLE rare, Malar ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Fibrinogen level, ↑ sIL ... Leishmaniosis, malaria ... lymphoma (DLBCL, intravascular ... treatment #summary #rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor and lupus ... Willebrand syndrome • Lupus ... , disseminated intravascular ... disease • Acute DIC ... Differential #Diagnosis #Hematology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
including systemic lupus ... cell lymphoma - Intravascular ... with interleukin (IL ... diagnosis #management #rheumatology
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