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diagnosis hematology causes erythematosus hemolytic management sle systemic autoantibodies bleeding extravascular hemolysis hemostasis hodgkins intravascular lymphoma mimickers oncology pediatrics peds
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... Bartonella, Babesia, Malaria ... Diagnosis #causes #classification ... #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... - Hemolytic anemia ... (aPL) 30-45% Differential ... symptoms #mimickers #differential ... #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... • Infections: Malaria ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Photosensitivity • Malar ... lymphopenia, low PLT • Anemia
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... of Hemostasis - Differential ... inhibitor and lupus ... of factor VII should ... #Bleeding #Bruising
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Purpura or Easy Bruising ... SLE (systemic lupus ... - Bernard—Soulier ... Scurvy #Purpura #Bruising ... pediatrics #diagnosis #differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... -95% of cases) Classification ... Immunohistochemical studies (to differentiate ... #hematology #oncology
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
motion in the shoulders ... describe difficulty rising ... • Normocytic anemia ... normal and can help differentiate ... Diagnosis #Management #Rheumatology
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