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diagnosis differential hematology classification adverseeffects autoantibodies benefits bleeding erythematosus extravascular fever hcq hemolysis hemostasis hodgkins hydroxychloroquine infectiousdiseases intravascular lymphoma management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... usually IgG) (e.g. lupus ... • Infections: Malaria ... #anemia
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic ... : • Liver disease ... Bartonella, Babesia, Malaria ... classification #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... sclerosis, Still's disease ... #differential #rheumatology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... or Easy Bruising ... SLE (systemic lupus ... Congenital heart disease ... #Causes #peds #
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... Benefits: ↓ Disease ... limited) risk of hemolysis ... Risks #Benefits #Lupus ... #sideeffects #rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... inhibitor and lupus ... of factor VII should ... discern these causes ... #Bleeding #Bruising
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
No hemolytic anemia ... Babesiosis • Plasmodium ... of malaria diagnosed ... • Falciparum malaria ... diagnostic tests for malaria
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hematological malignancy arising ... Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... number of sites of disease
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