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diagnosis differential hematology bruising extravascular hemolysis hemolytic table algorithm bleeding classification druginduced hemostasis management pediatrics peds pericarditis presentation purpura signs
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... usually IgG) (e.g. lupus ... • Infections: Malaria ... #diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Infections • Malaria ... immune-complex hemolytic anemia ... Diagnosis #Algorithm #Causes ... #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... Bartonella, Babesia, Malaria ... IVIG infusion Intravascular ... #Hemolytic #Anemia ... classification #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
& NPSLE rare, Malar ... Discontinuation of causal ... Manifestations: Malar ... #sle #comparison ... #table #rheumatology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
associated with rheumatologic ... presentation of systemic lupus ... trapezius ridges or shoulders ... life-threatening causes ... #Presentation #comparison
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 Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... SLE (systemic lupus ... (disseminated intravascular ... - Bernard—Soulier ... Purpura #Bruising #Causes
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor and lupus ... Willebrand syndrome • Lupus ... of factor VII should ... , disseminated intravascular ... discern these causes
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