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differential hematology sle erythematosus management signs systemic table oncology classification druginduced vasculitis aplastic arthritis autoantibodies cold dil extravascular hemolysis hemolytic
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... rash 40% - Fever ... - Hemolytic anemia ... autoantibodies #signs #symptoms ... #differential #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... usually IgG) (e.g. lupus ... • Infections: Malaria ... #hematology #anemia
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
& NPSLE rare, Malar ... Discontinuation of causal ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: Fever ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Typical Signs/Symptoms ... Alopecia, Fever ... , Malar rash, Photosensitivity ... Erythematosus #SLE #Signs #Symptoms ... #diagnosis #rheumatology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
associated with rheumatologic ... life-threatening causes ... #Pericarditis #Symptoms ... #Presentation #comparison ... #Table #Diagnosis
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 Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... and duration of symptoms ... - Headache, fever ... #rheumatology # ... comparison #table
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... and petechiae Causes ... • Improve the symptoms ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Photosensitivity • Malar ... lymphopenia, low PLT • Anemia ... : • Symptoms limited ... #Rheumatology
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
No hemolytic anemia ... Babesiosis • Plasmodium ... of malaria diagnosed ... and myalgias, symptoms ... tests for malaria
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