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diagnosis management arthritis joint disease signs sle comparison erythematosus msk treatment workup anemia approach causes classification druginduced hemolytic myopathy myositis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint Pain ... B19 infection Malar ... lesions • Discoid lupus ... #rashes #differential ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... Auto-Antibodies: - ANA ... Diagnosis and Lupus ... autoantibodies #signs #symptoms ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... should be interpreted ... context of other symptoms ... #patterns #rheumatology ... #diagnosis #differential
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
Features That Differentiate ... associated with rheumatologic ... presentation of systemic lupus ... trapezius ridges or shoulders ... #Pericarditis #Symptoms
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 Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... & NPSLE rare, Malar ... Manifestations: Malar ... Workup: - ANA ... comparison #table #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Rheumatica • Pain ... Diffuse muscle pain ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
common sites: hip, shoulder ... XR, MRI to dx and ... • Differentiate ... SickleCell #Disease #differential ... diagnosis #causes #hematology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... Inflammatory joint pain ... fingers, or pain ... the face (many differential ... erythematosus #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Arthritis: • Joint pain ... Photosensitivity • Malar ... : • Symptoms limited ... Erythematosus #Diagnosis #Rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... • Infections: Malaria ... disease, Copper and ... Extravascular #Causes #differential ... #diagnosis #hematology
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