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diagnosis hematology causes joint arthritis disease erythematosus workup antinuclear hemolytic management msk patterns signs symptoms systemic thrombocytopenia vasculitis activation agglutinin
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... #Antinuclear #Antibodies ... #ANA #patterns ... #rheumatology #diagnosis ... #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... Auto-Antibodies ... : - ANA 95-100% ... Diagnosis and Lupus ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... assay (IFA) is the main ... should be interpreted ... #rheumatology #diagnosis ... #differential
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint Pain ... B19 infection Malar ... lesions • Discoid lupus ... #skin #rashes #differential ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Arthritis: • Joint pain ... Photosensitivity • Malar ... lymphopenia, low PLT • Anemia
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... fingers, or pain ... the face (many differential ... #diagnosis #sle ... erythematosus #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... • Infections: Malaria ... disease, Copper and ... Extravascular #Causes #differential ... #anemia
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
common sites: hip, shoulder ... XR, MRI to dx and ... dz difficult to see ... • Differentiate ... diagnosis #causes #hematology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
Features That Differentiate ... associated with rheumatologic ... presentation of systemic lupus ... trapezius ridges or shoulders ... it difficult to differentiate
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 Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... erythematosus (SLE ... #Diagnosis #rheumatology
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