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diagnosis management differential erythematosus dermatology systemic arthritis syndrome druginduced msk oncology summary vasculitis workup activation algorithm ana antibodies antinuclear antinxp2
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Pain Rash ... B19 infection Malar ... lesions • Discoid lupus ... #joint #pain #skin ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Manifestations: Malar ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Cell Disease Vaso-occlusive ... common sites: hip, shoulder ... dz difficult to see ... #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
& NPSLE rare, Malar ... Manifestations: Malar ... life-threatening • Treatment ... Evolution: Chronic disease ... #table #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... lesions Abdominal pain ... (20%) Renal disease ... symptoms #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... autoantibodies that will cause ... Erythematosus #SLE ... CNS #neurology #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Arthritis: • Joint ... pain • Swan neck ... Photosensitivity • Malar ... Erythematosus #Diagnosis #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... healthy adults, and should ... erythematosus (SLE ... : Lupus (SLE), Systemic ... ANA #patterns #rheumatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... and these should ... neurology, back pain ... Rheumatology ... discrepancy, multiple joint
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