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diagnosis management sle druginduced erythematosus systemic ana antibodies antinuclear antiphospholipid apls arthritis comparison differential dil disease fever fuo hypercoagulable laboratory
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... & NPSLE rare, Malar ... • Immunologic Workup ... comparison #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar ... • Immunologic Workup ... Management #Summary #rheumatology
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
• CNS symptoms ... Returning Traveler’ algorithm ... • Travel to malaria–endemic ... node biopsy • Clinical ... values supporting hematologic
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
healthy adults, and should ... context of other symptoms ... likely it will be clinically ... , Drug-induced Lupus ... ANA #patterns #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Non-autoimmune rheumatologic ... Photosensitivity • Malar ... : • Symptoms limited ... Erythematosus #Diagnosis #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Constitutional symptoms ... & NPSLE rare, Malar ... • Immunologic Workup ... #DIL #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... ANAs RF test should ... ANA and RF (if clinical ... diagnosis #testing #Rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup ... Algorithm INDICATIONS ... - 1 or more clinical ... excluded Testing: • Lupus ... #hematology
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