12 results
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
: - Arthritis ... 69% - Malar rash ... and Lupus Mimickers ... autoantibodies #signs #symptoms ... #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint ... Pain - Diagnostic ... spondyloarthropathies, lupus ... #rheumatology # ... approach #workup
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Approach to Joint ... or nerve root Symptoms ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... B19 infection Malar ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... of hip (rare), Arthritis ... in small joints ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Typical Signs/Symptoms ... Alopecia, Fever, Malar ... , Arthralgia / arthritis ... Erythematosus #SLE #Signs #Symptoms ... #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Approach to Joint ... Differential Diagnosis ... constitutional symptoms ... #Diagnosis #MSK ... #rheumatology #
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... , Arthritis, myalgia ... & NPSLE rare, Malar ... comparison #table #rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... : • Joint pain ... Photosensitivity • Malar ... : • Symptoms limited ... #Rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
neutrophilic dermatosis (Sweets ... inflammation of the joints ... and pain of the joints ... development of skin symptoms ... ’s syndrome - Lupus