125 results
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
representing thrombin-platelet ... - Treatment: Platelets ... Thromboelastogram #TEG ... Thromboelastography #diagnosis #coagulation
Thromboelastography (trademarked as TEG)
 • Graphical representation of the fibrin polymerization process
 • Point-of-care anti-coagulation monitoring
trademarked as TEG ... Point-of-care anti-coagulation ... amplitude • If ↓ → platelet ... deficiency → give platelets ... Thromboelastogram #TEG
THROMBOELASTOGRAPHY (TEG)
General Principle
• A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
THROMBOELASTOGRAPHY (TEG ... problems with coagulation ... cascade and platelet ... @nickmmark #TEG
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
Thromboelastography (TEG ... cryoprecipitate - If platelets ... < 50 -> platelet ... Thromboelastography #TEG
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
Thromboelastography (TEG ... cryoprecipitate If platelets ... < 50 - > platelet ... Thromboelastography #TEG
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... • Absence of platelet
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... concentrate - Platelets ... Hct < .005) Platelet ... pheresis - Platelets
A Classification of Coagulation Disorders

#Coagulation #Disorders #Classification #Platelet #Classification #Differential #Diagnosis
Classification of Coagulation ... Disorders #Coagulation ... Classification #Platelet
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... ristocetin • Normal platelet ... count and platelet ... • Platelet flow ... Usually normal platelet
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
children) • Platelets ... extremely low platelet