2778 results
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... Laboratory • Normal platelet ... factor VIII) Treatment ... VonWillebrand #Disease
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Thrombocytosis #Platelets
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... • Severe Liver Disease ... + Bleeding Treatment ... diagnosis #causes #treatment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
to a low blood platelet ... Myeloproliferative Disease ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Blood (platelets ... the absence of treatment ... against T. cruzi Treatment ... q12h)x 60 days Treatment ... Diagnosis #Management #Treatment
Mild-to-Moderate Ulcerative Colitis - Management Algorithm
Curcumin:
 • Natural phytochemical from turmeric
 • 2g/day divided in 2-3
injury, inhibit platelet ... dosing if liver disease ... Moderate #Algorithm #treatment
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... elevation of ALT, platelets ... echo is positive, treatment ... Pediatrics #Kawasaki #Disease
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... ristocetin • Normal platelet ... count and platelet ... • Platelet flow ... Von Willebrand Disease
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... • Absence of platelet
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
cryoprecipitate If platelets ... < 50 - > platelet ... Thromboelastogram #Treatment