26 results
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Idiopathic Thrombocytopenic ... Menorrhagia • GI bleeding ... children) • Platelets ... only for severe bleeding ... extremely low platelet
Indications for Transfusion
Packed RBCs
 • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
• < 30,000 and bleeding ... in setting of thrombocytopenic ... heparin-induced thrombocytopenia ... in idiopathic thrombocytopenic ... • Thrombotic thrombocytopenic
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... , Large platelets ... chain IIA • Thrombocytopenia ... fibrinogen) • Thrombocytopenia ... #Defects #comparison
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Bleeding and Bruising ... Differential Diagnosis Algorithm ... vs Acquired • Platelet ... Quantitative (Thrombocytopenia ... vs Acquired #Bleeding
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Heparin-Induced Thrombocytopenia ... Suspected HIT Algorithm ... (platelet count ... Timing of onset of platelet ... diagnosis #4Ts #algorithm
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia ... Differential Diagnosis Algorithm ... MatthewHoMD #Thrombocytopenia ... Differential #Diagnosis #Algorithm ... #hematology #platelets
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Thrombocytopenia ... Sequestration Disordered Platelet ... Coagulation #Bleeding
Algorithm for diagnosis of familial thrombocytopenia. Platelet size, best determined by review of the peripheral smear,
Algorithm for diagnosis ... of familial thrombocytopenia ... Platelet size, best ... Hematology #Familial #Thrombocytopenia ... #Algorithm
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... History: - Prior platelet ... - History of bleeding ... epistaxis, gingival bleeding ... #Platelet #Disorders
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
transfusion • Thrombocytopenia ... Findings in DIC: • Platelet ... DITMA) - MAHA + Thrombocytopenia ... - Platelet rich ... coagulopathy - Thrombocytopenia