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diagnosis hematology differential causes bruising petechiae acute afib aki anticoagulation aptt blanching bleed bluebloaters bruise chads2 chads2vasc copd dermatology dic
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Destruction • Abnormal ... Sequestration Disordered Platelet ... #Bleeding #Bruising
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Bleeding and Bruising ... Differential Diagnosis Algorithm ... vs Acquired • Platelet ... Qualitative • Coagulation ... vs Acquired #Bleeding
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... DrEricStrong #Algorithm ... #Coagulation #Abnormal ... Hematology #Diagnosis #Workup
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Prolonged PTT, Normal ... PT (INR) - Bleeding ... PT (INR) - No Bleeding ... Differential #Diagnosis #Algorithm ... Causes #Hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Qualitative defect in platelets ... characteristic of a platelet ... inhibitor of a coagulation ... PT/ABNORMAL PTT ... intravascular coagulation
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
are typical of coagulation ... lowest levels Platelet ... , PT should be normal ... ability to bind platelets ... Measurement of coagulation
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Algorithm and Differential ... investigations abnormal ... fragmentocytes, LDH, platelets ... #Injury #AKI #Workup
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... platelet function ... deficiency - Abnormal ... deficiency Work ... Complete blood count coagulation
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... properly, leading ... unusual bruising or bleeding ... are caused by bleeding ... Workup: • Complete
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