43 results
diagnosis hematology management differential comparison thrombocytopenia algorithm pharmacology causes disorders pathophysiology reactions transfusion anticoagulation antiplatelet bruising pregnancy risk thresholds types
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... Defects #comparison #table
Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
Menorrhagia • GI bleeding ... children) • Platelets ... only for severe bleeding ... extremely low platelet
Indications for Transfusion Packed RBCs • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
hemoglobinopathy Platelets ... Prophylactically for platelet ... not transfuse platelets ... Platelet transfusions ... Management #RBCs #Platelets
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... concentrate - Platelets ... Hct < .005) Platelet ... pheresis - Platelets
Thresholds for Transfusion of Platelets in Adults Major surgery or invasive procedure, no active bleeding - ≤
Transfusion of Platelets ... procedure, no active bleeding ... Surgery with active bleeding ... 100 (rarely) Stable ... #Management #Platelets
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 A Classification of Coagulation Disorders #Coagulation #Disorders #Classification #Platelet #Classification #Differential #Diagnosis
A Classification ... Coagulation #Disorders #Classification ... #Platelet #Classification
Summary of characteristics of Platelet Aggregation Inhibitors #AntiPlatelet #Inhibitors #Pharmacology #Table #Overview #Interactions #Pharmacology #Cardiology
characteristics of Platelet ... #Pharmacology #Table
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Bleeding and Bruising ... vs Acquired • Platelet ... vs Acquired #Bleeding
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... bruising • Skin bleeding ... • Prolonged bleeding ... Laboratory • Normal platelet
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease Increased Thrombosis Increased Platelet-Vesset Wall Interaction •
Thrombosis and Bleeding ... Thrombosis Increased Platelet-Vesset ... #Thrombosis #Bleeding
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