59 results
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... ristocetin • Normal platelet ... count and platelet ... • Platelet flow ... considered first-line testing
Indications for Transfusion
Packed RBCs
 • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
hemoglobinopathy Platelets ... Prophylactically for platelet ... not transfuse platelets ... Platelet transfusions ... Management #RBCs #Platelets
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Differential Diagnosis Algorithm ... hematology for workup ... Thrombocytosis #Platelets ... Differential #Diagnosis #Algorithm
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Differential Diagnosis Algorithm ... < 1800/uL, • platelet ... /uL Initial Workup ... Differential #Diagnosis #Algorithm ... #hematology #workup
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Suspected HIT Algorithm ... Thrombocytopenia (platelet ... Timing of onset of platelet ... diagnosis #4Ts #algorithm
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Thrombocytopenia and Platelet ... Diagnosis and Workup ... History: - Prior platelet ... smear, HIV/HCV testing ... Thrombocytopenia #Platelet
Thrombocytopenia 
Work up, differential diagnosis and management.

Satyendra Dhar MD, @DharSaty

#thrombocytopenia #platelets #ITP #DIC
Thrombocytopenia Work ... thrombocytopenia #platelets
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Differential Diagnosis Algorithm ... vs Acquired • Platelet ... Differential #Diagnosis #Algorithm
Algorithm for diagnosis of familial thrombocytopenia. Platelet size, best determined by review of the peripheral smear,
Algorithm for diagnosis ... Platelet size, best ... Thrombocytopenia #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... with or without platelet ... Differential #Diagnosis #Algorithm ... #workup #hematology ... #testing