31 results
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... count and platelet ... (either severe Type ... 1 or Type 3) — ... considered first-line testing
Indications for Transfusion
Packed RBCs
 • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
hemoglobinopathy Platelets ... Prophylactically for platelet ... not transfuse platelets ... Platelet transfusions ... #RBCs #Platelets
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Differential Diagnosis Algorithm ... Congenital vs Acquired ... • Platelet Defect ... Congenital vs Acquired ... Differential #Diagnosis #Algorithm
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Differential Diagnosis Algorithm ... Sequestration Disordered Platelet ... Vascular System - Acquired ... Coagulation Proteins - Acquired ... Differential #Diagnosis #Algorithm
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Thrombocytopenia and Platelet ... History: - Prior platelet ... smear, HIV/HCV testing ... evaluation: not required ... Thrombocytopenia #Platelet
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
coagulation and other testing ... (platelet count ... D-dimer, egg) are required
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Qualitative defect in platelets ... characteristic of a platelet ... (variable)* • Acquired ... XI, or XII • Acquired ... fibrinogen levels, and testing
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
to a low blood platelet ... neutrophils and platelets ... Neutropenia • Platelet ... blood cells or platelets ... blood cells or platelets
Thromboelastography (trademarked as TEG)
 • Graphical representation of the fibrin polymerization process
 • Point-of-care anti-coagulation monitoring
routine transfusion algorithms ... of transfusions required ... amplitude • If ↓ → platelet ... deficiency → give platelets
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
donor (apheresis) platelets ... transfusion, due to anti-platelet ... common following platelet ... contamination: Platelets ... Transfusions #diagnosis #management