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diagnosis differential management hematology nephrology neurology pediatrics peds dermatology workup endocrinology obgyn treatment cardiology ddxof acute obstetrics hepatology thrombocytopenia chronic
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Evidence Summary for Transfusion ... unnecessary and cause ... Unnecessary transfusions ... Transfusions should ... Transfusions are
Indications for Transfusion Packed RBCs • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
Indications for Transfusion ... hemoglobinopathy Platelets ... not transfuse platelets ... Platelet transfusions ... Willebrand disease #Transfusion
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
donor (apheresis) platelets ... , due to anti-platelet ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Indications for Transfusion of Platelets in Neonates #Management #Peds #Pediatrics #Platelets #Transfusion #Plateletpheresis #Thresholds #NonBleeding #Surgery
Indications for Transfusion ... of Platelets in ... Peds #Pediatrics #Platelets ... #Transfusion #Plateletpheresis
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 Thromboelastography (TEG) based therapy and Management If r time prolonged -> FFP If MA low -> plts/cryoprecipitate (if
cryoprecipitate If platelets ... < 50 - > platelet ... transfusions If
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
, due to anti-platelet ... Causes purpura & ... TRALI): Leading cause ... common following platelet ... more likely to cause
Thromboelastography (TEG) Based Management - If R time prolonged -> FFP - If MA low
cryoprecipitate - If platelets ... < 50 -> platelet ... transfusions
Thromboelastography (trademarked as TEG) • Graphical representation of the fibrin polymerization process • Point-of-care anti-coagulation monitoring
determining if transfusion ... algorithms and ... reduce number of transfusions ... amplitude • If ↓ → platelet ... deficiency → give platelets
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Differential Diagnosis Platelet ... Differential #Diagnosis #causes ... #Platelets #hematology
Thresholds for Transfusion of Platelets in Adults Major surgery or invasive procedure, no active bleeding - ≤
Thresholds for Transfusion ... of Platelets in ... #Management #Platelets ... #Transfusion #Plateletpheresis
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