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diagnosis differential management hematology algorithm clinical treatment pathophysiology classification nephrology criticalcare gastroenterology pediatrics pharmacology workup comparison pulmonary table thrombocytopenia anemia
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
donor (apheresis) platelets ... Causes purpura & ... cause of transfusion ... coagulopathy & ↑bleeding ... more likely to cause
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
, due to anti-platelet ... Causes purpura & ... cause of transfusion ... common following platelet ... more likely to cause
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
incompatible blood transfusion ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... Treat primary cause ... hydration • RBC transfusion
Indications for Transfusion Packed RBCs • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
Indications for Transfusion ... • < 30,000 and bleeding ... postoperative bleeding ... Platelet transfusions ... Willebrand disease #Transfusion
Thresholds for Transfusion of Platelets in Adults Major surgery or invasive procedure, no active bleeding - ≤
Thresholds for Transfusion ... of Platelets in ... procedure, no active bleeding ... #Management #Platelets ... #Transfusion #Plateletpheresis
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 Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Evidence Summary for Transfusion ... unnecessary and cause ... Unnecessary transfusions ... Transfusions should ... Transfusions are
Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
Menorrhagia • GI bleeding ... children) • Platelets ... only for severe bleeding ... extremely low platelet
Indications for Transfusion of Platelets in Neonates #Management #Peds #Pediatrics #Platelets #Transfusion #Plateletpheresis #Thresholds #NonBleeding #Surgery
Indications for Transfusion ... of Platelets in ... Peds #Pediatrics #Platelets ... #Transfusion #Plateletpheresis
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 Thromboelastography (TEG) based therapy and Management If r time prolonged -> FFP If MA low -> plts/cryoprecipitate (if
cryoprecipitate If platelets ... < 50 - > platelet ... transfusions If
Thromboelastography (TEG) Based Management - If R time prolonged -> FFP - If MA low
cryoprecipitate - If platelets ... < 50 -> platelet ... transfusions
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