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diagnosis differential management hematology nephrology neurology cardiology workup clinical evaluation treatment acute anemia criticalcare dermatology echocardiogram peripheral weakness blood cardiac
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Evidence Summary for Transfusion ... NEJM 1999 - ICU FOCUS ... unnecessary and cause ... Transfusions should ... Transfusions are
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
donor (apheresis) platelets ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... , Trypanosoma (Chagas
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
, due to anti-platelet ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... , Trypanosoma (Chagas
Thromboelastography (trademarked as TEG) • Graphical representation of the fibrin polymerization process • Point-of-care anti-coagulation monitoring
determining if transfusion ... algorithms and ... reduce number of transfusions ... amplitude • If ↓ → platelet ... deficiency → give platelets
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... and Platelet Disorders ... History: - Prior platelet ... neurologic/psychiatric changes ... Thrombocytopenia #Platelet
PLATELETS Mnemonic for Causes of Thrombocytopenia P - Platelet Disorders (DIC, ITP, TTP) L - Leukemia, Lymphoma A -
PLATELETS Mnemonic ... for Causes of Thrombocytopenia ... P - Platelet ... Anemia T - Trauma, Transfusion ... S - Sepsis #PLATELETS
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
and Extrinsic Causes ... autoimmune (most of the causes ... hemolysis, hemolytic transfusion ... Differential #Diagnosis #Causes ... #Algorithm
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
incompatible blood transfusion ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... Treat primary cause ... hydration • RBC transfusion
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm With Sensory Changes:
Causes of Peripheral ... Without Sensory Changes ... Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #Causes
Approach to Hemorrhagic Shock PLAN FOR CONTROLLING HEMORRHAGE & ACTIVATE MASSIVE TRANSFUSION PROTOCOL • Activate massive transfusion
ACTIVATE MASSIVE TRANSFUSION ... Activate massive transfusion ... 1 RBC/1 FFP/1 platelet ... • Can use CBC, coags
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