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management diagnosis diabetes dm2 endocrinology medications toxicity acetaminophen agonists aliem amiodarone classes clozapine differential drugs ecg fomepizole glp1 induced ingestion
Common sodium channel blockers which cause QRS widening. Anticonvulsants: - Carbamazepine Antidysrhythmics: - Group
blockers which cause ... QRS #widening #ECG ... #EKG #Pharmacology ... #Medications #Toxicology ... Differential #Drugs #Classes
Vasopressors and Inotropes - Pharmacology Summary Vasopressors Phenylephrine (alpha-1) • Increases BP, SVR • Risk of reflex bradycardia
and Inotropes - Pharmacology ... Summary Vasopressors ... • Higher doses cause ... cAMP/cGMP • Causes ... #Summary #management
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Summary Mechanisms ... agent • Does not cause ... side effects (e.g ... #Summary #DM2 #
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... Summary Mechanisms ... side effects (e.g ... not definitively cause ... #Summary #DM2 #
Naloxone - Toxicology Adult starting dose: - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients - 0.04 mg
Naloxone - Toxicology ... dose: - 0.1 mg/kg ... search for other causes ... Naloxone #Narcan #Toxicology ... #Management #Pharmacology
Clozapine Toxicology Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... distribution (1.6 – 7 L/kg ... Clozapine is known to cause ... #Clozapine #Toxicology ... Toxicity #Diagnosis #Pharmacology
Toxic Alcohol Ingestion: Methanol Solvent found in cleaning and printing solutions, adhesives, stains, paint removers, antifreeze agent in
gasoline additive Pharmacology ... dose = 1-2 mL/kg ... . formic acid) causes ... , but does NOT cause ... Diagnosis #Management #Toxicology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Lung Toxicity Summary ... Acute toxicity (e.g ... Chronic toxicity (e.g ... Exclude other causes ... diagnosis #management #Toxicology
Fomepizole for Acetaminophen Toxicity • In cases where fomepizole and NAC were administered together, evidence has
Toxicity • In cases ... has come from case ... over 500-600 mg/kg ... Acetaminophen #Toxicology ... #pharmacology #
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